Opioids

Cerebral Blood Flow Effects of Acute Intravenous Heroin Administration

Kosel M, Noss RS, Hämmig R, Wielepp JP, Bundeli P, Heidbreder R, Kinser JA, Brenneisen R, Fisch HU, Kayser S, Schlaepfer TE (2008): Cerebral Blood Flow Effects of Acute Intravenous Heroin Administration. European Journal of Neuropharmacology 18:278-85.

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Pattern of regional cerebral blood-flow changes induced by acute heroin administration - a perfusion MRI study

Guyer S, Kosel M, Altrichter S, El-Koussy M, Haemmig R, Fisch HU, Lovblad KO, Schlaepfer TE (2007): Pattern of regional cerebral blood-flow changes induced by acute heroin administration - a perfusion MRI study. J Neuroradiol 34:322-329.
PMID: 18022231
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Decreased frontal white-matter volume in chronic substance abuse

Schlaepfer TE, Lancaster E, Heidbreder R, Strain E, Kosel M, Fisch HU, et al (2006). Decreased frontal white-matter volume in chronic substance abuse. International Journal of Neuropsychopharmacology 9(2): 147-153.
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SPECT brain blood flow changes with continuous ligand infusion during previously-learned WCST performance

Tien AY, Schlaepfer TE, Orr W, Pearlson GD: SPECT brain blood flow changes with continuous ligand infusion during previously-learned WCST performance. Psychiatry Research-Neuroimaging 82(1):47-52, 1998
PDF A26

The site of opioid action in the human brain: mu and kappa agonists produce different subjective and cerebral blood flow effects

Schlaepfer TE, Strain EC, Greenberg BD, Preston KL, Lancaster E, Bigelow GE, Barta PE, Pearlson GD: The site of opioid action in the human brain: mu and kappa agonists produce different subjective and cerebral blood flow effects. American Journal of Psychiatry 155:470-473, 1998
PDF A24