2007

hERG binding data

Given the issues that many drug discovery programs have had with off-target activity at the hERG channel I've started to compile a database of literature binding data Read More...

Added search box

Added search box Read More...

Drug Discovery Resources Update

I updated the metal chelation pages and added a page on aromatic ring bioisosteres. Read More...

Metal Chelation

More on metal chelation Read More...

Brain Penetration

Some thoughts about brain penetration. Read More...

Added Metabolism section

I've now updated section on ADME properties to include possible strategies to reduce metabolism.
Drug Discovery Resources

Started ADME section

I've now started a section on ADME properties Read More...

Drug Discovery Resources

Resources for Medicinal Chemists Read More...

Chemistry Central Blog

A blog for Open Access chemistry Read More...

Resources for Drug Discovery

A compilation of resources for Drug Discovery Read More...