Higher Education:

1984-1987 B.Sc. (Hons) Biochemistry IIi, University of Sheffield

1987-1991 Ph.D. in Biochemistry, University of Sheffield ‘The DNA (cytosine-5) methyltransferase from human cells’
Supervisor: Dr. D.P. Hornby

Research Positions:

1992 -1993 Postdoctoral Research Assistant, Andrology Research Institute & Department of Molecular Biology, University of Sheffield.
Funding: Sheffield University Research Fund. Supervisor: Dr. C.L.R. Barratt.
Research project: Expression of human zona pellucida sperm receptor, ZP3 in bacterial and mammalian cell systems.

1993 - 1996 Post-doctoral Research Assistant (RA1A)
Department of Biochemistry, University of Dundee.
Advisor: Dr. M.J.R. Stark
Research project: The role of Saccharomyces cerevisiae protein phosphatase 1 in growth and division: characterisation of regulatory inhibitory polypeptides responsible for its essential function.

1996–2000 Post-doctoral Research Assistant (RA1A)
Department of Biochemistry, University of Dundee
Advisor: Dr. M.J.R.Stark
Research project: A molecular analysis of the mitotic requirement for type-1 protein phosphatase (PP1) in the yeast Saccharomyces cerevisiae

2000-2002 Senior Research Scientist & DeltaVision Microscope Facility Manager Wellcome Trust Biocentre, Division of Gene Regulation and Expression, School of Life Sciences, University of Dundee Trust
Advisor: Dr. Jason R. Swedlow
Human Aurora B kinase. Developing deconvolution microscopy in Dundee

2002-2006 Senior Research Scientist (RAII) Wellcome Trust Biocentre
Division of Gene Regulation and Expression, School of Life Sciences, University of Dundee
Advisors: Professor A. I. Lamond and Dr. J. R. Swedlow

2006-2007 NESTA Crucible Fellow, Consultant and Freelance Writer

2007- Senior Scientist, ITI Stem Cell Technology Programme, Drug Discovery Unit, College of Life Sciences, James Black Centre, University of Dundee.
Lab Head: Professor Julie Frearson

 

Click Here for Publications:

 

Invited Oral Presentations ’93-‘05:

1. Yeast Cell Biology Meeting, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA (1993). Analysis of protein phosphatase-1 function in Saccharomyces cerevisiae.

2. 6th Meeting of the Scottish Signal Transduction Group, Edinburgh, UK (1993). Function of protein phosphatase-1 in Saccharomyces cerevisiae.

3. British Yeast Group Meeting, University of Sheffield (1994). Functions of protein phosphatase-1 in Saccharomyces cerevisiae.

4. Biochemistry Department Seminar, University of Dundee (1994). Genetic Analysis of PP1 function in budding yeast.

5. MRC Protein Phosphorylation Unit Symposium, Dundee (1996) Novel functions of PP1 in budding yeast.

6. MRC Protein Phosphorylation Unit Symposium, Dundee (1996) PP1 regulatory subunits in budding yeast.

7. Dundee Cell Biology Club (1998) The role of PP1 in yeast cell growth and division.

8. British Yeast Group Meeting, Aberdeen (2000) Dynamic, Rho1-dependent localisation of Pkc1p to polarised growth sites in budding yeast.

9. Scottish Microscopy Group, Glasgow (2001) Critical Comparison of Wide Field and Confocal Microscopes in Fluorescence Live Cell Imaging.

10. Division of Gene Regulation and Expression, School of Life Sciences, University of Dundee (2002). Watching a chromosomal passenger protein in action: Spatio-temporal Dynamics of human Aurora B Protein Kinase.

11. British Society for Cell Biology Meeting, York, UK (April 2002) Spatial and Temporal Dynamics of Aurora B Protein Kinase in Living HeLa Cells.

12. Department of Physiology and Biophysics, University of Washington, Seattle, USA. (May 2002). Aurora B – analysis of dynamics and roles in kinetochore-microtubule function.

13. 1st Dundee Aurora B minisymposium 2003, Sandford Hotel, Fife (Dec 2003) Aurora B Protein Kinase Regulates the Microtubule Destabilizing Kin I Kinesin, MCAK.

14. IBLS, University of Glasgow, UK, (March 2004) Aurora B Regulates the Localisation and Activity of the Pac-Man kinesin, MCAK.

15. 8th International Congress of Cell Biology/European Life Scientist Organisation (Sept 2004), Nice, France. Aurora B Regulates MCAK’s Microtubule Depolymerisation Activity and Localisation at the Mitotic Centromere.

16. Division of Gene Expression and Regulation Seminar Series, University of Dundee, UK. (Nov. 2004) Controlling the Pac-Man Kinesin: Aurora B Regulates MCAK at the Mitotic Centromere.

17. Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. (Dec 2004) Aurora B Protein Kinase and the Microtubule Depolymerising Kinesin MCAK: a Dynamic Kinase Controlling a Dynamic Substrate.

 

 

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