abortions, death.", "Swelling, pruritis, shock (dilated pupils, respiratory paralysis) from reaction to dead microfilaria - prevent with a glucocorticoid. Larva killed in vertebral canal can cause paralysis/staggering. Sometimes produces acute toxic reactions.", "Relatively nontoxic. May slightly irritate skin.", "Risk of neurotoxicity. Use this agent only as a second-line treatment for patients who are intolerant/unresponsive to other treatments.", "Acute dermal toxicity level for rabbits: LD50 (24hr) = 4100 mg/kg. Antidotes: atropine sulfate, pralidoxime. Symptoms of acute organophosphate poisoning: headache, dizziness, weakness, incoordination, muscle twitching, tremor, nausea, abdominal cramps, diarrhea, blurred/dark vision, confusion, toxic psychosis, respiratory depression, wheezing, cough, and pulmonary edema. incontinence, unconsciousness and convulsions indicate very severe poisoning. Slow heartbeat, salivation, and tearing are common.", "Abdominal pain & diarrhea in cases of massive infection/expulsion of worms. Cimetidine may increase plasma concentration of mebendazole. Monitor hematopoietic and hepatic organ system function.", "Disturbances of the GI tract such as nausea, retching and abdominal pain.", "Nausea, vomiting, abdominal cramps, diarrhea, CNS disturbances. Avoid administering to nursing mothers, patients with impaired kidney or liver function, convulsive disorders, or a history of hypersensitivity reactions to piperazine or its salts. Concomitant administration with phenothiazines may increase extrapyramidal effects (including violent convulsions).", "Nausea, vomiting, abdominal cramps, diarrhea, CNS disturbances. Avoid administering to nursing mothers, patients with impaired kidney or liver function, convulsive disorders, or a history of hypersensitivity reactions to piperazine or its salts. Concomitant administration with phenothiazines may increase extrapyramidal effects (including violent convulsions).", "Tends to sting at the injection site, pet may scratch at the site or cry immediately following injection. Oral form is bitter tasting. Nausea, weakness, salivation, after a tapeworm injection are less common.", "Acute toxicity: skin irritation, itching, pricking sensations, local burning sensations, tongue and lip numbness, nausea, and diarrhea, aggressive sparring, incoordination, tremors, convulsions, paralysis, respiratory failure, and death.", "Aids in the prevention of coccidiosis. Do not to feed to pregnant/nursing animals.", "Alt. Route: 50 mg/kg loading dose, then 25 mg/kg.\rAvoid administering to patients showing marked liver parenchymal damage or blood dyscrasias. Symptoms of toxicity similar to those of TMP-SMZ: possible (irreversible) keratoconjunctivitis sicca, hepatitis, vomiting, anorexia, diarrhea, etc.", "All sulfa drugs are somewhat toxic, producing blood abnormalities and kidney damage when indiscriminately used.", "Alt. Route: 1 g/L (.10-.15%) drinking water.\rDANGER: used as a rodenticide. In 1991, the EPA banned products containing N-(2-Quinoxalinyl) sulfanilamide.", "Possible oral toxicity - topical application preferred. Thiabendazole should not be used to treat mixed infections with ascaris (roundworm) because it can cause the worms to migrate. Causes toxemia at high doses in ewes.", "See -More Drug Info-", "See -More Drug Info-", "See -More Drug Info-", "See -More Drug Info-", "See -More Drug Info-", "Use low dose if debilitated/geriatric/obese.", "Use low dose if debilitated/geriatric/obese.", "See -More Drug Info-", "See -More Drug Info-", "Use low dose if debilitated/geriatric/obese.", "Alt. Route: 1-5 mg/kg IV\n\nDiazepam Doses (mg/kg)\nIM/IV\n1. 5-10 / 1-5\n2. 1-2 / 1-2\n3. 1-5 / -\n4. - / 1\n5. 0.5-2.5 / 0.5-2.5\n6. 5-10 / -\n7. 1-3 / - or\n 1-5 / 1-5 or\n 5-10 / -\n\n1. Biology of the Laboratory Rabbit\n2. Textbook of Rabbit Medicine (Harcourt-Brown)\n3. Ferrets Rabbits and Rodents (H & Q)\n4. Veterinary Drug Handbook (Plumb)\n5. Pharmaceutical Index (Willowbrook)\n6. Exotic Animal Formulary (AAHA)\n7. Exotic Animal Formulary (Carpenter et al.)", "See -More Drug Info-", "Alt. Route: 15-20 mg/kg IV", "Use low dose if debilitated/geriatric/obese.", "Alt. Route: 10mg/kg ketamine + 3mg/kg xylazine IV", "See -More Drug Info-", "Use low dose if debilitated/geriatric/obese.", "Use low dose if debilitated/geriatric/obese.", "Use low dose if debilitated/geriatric/obese.", "Use low dose if debilitated/geriatric/obese.", "Use low dose if debilitated/geriatric/obese.", "See -More Drug Info-", "Use low dose if debilitated/geriatric/obese.", "Use low dose if debilitated/geriatric/obese.", "Terminal use only.", "The reversal agent is yohimbine (0.2 mg/kg IV).", "See -More Drug Info-", "Recommended dose is high. Start with 1 to 2 baby aspirin (81-162 mg) per day to treat arthritis pain (approximately 30-60 mg/kg), then increase the dose as needed to give the bunny adequate pain relief. If the bunny starts to experience stomach pain, stagger the aspirin 3-6 hours apart with the anti-ulcer drug sucralfate (Carafate): 1/4 tablet (250 mg) diluted with water in a feeding syringe orally every 8-12 hours. Sucralfate is a safe cytoprotective agent that coats ulcerated tissue and promotes healing.", "Tylenol is extremely toxic to the liver! No longer recommended for rabbits. Use aspirin.", "See -More Drug Info-", "Alt. Route: 2 mg/kg SC", "See -More Drug Info-", "See -More Drug Info-", "See -More Drug Info-", "Alt. Dosage: 5-10 mg/kg q2-3h", "See -More Drug Info-", "See -More Drug Info-", "See -More Drug Info-", "See -More Drug Info-", "Alt. Route: 15 mg/kg PO", "See -More Drug Info-", "Alt. Route: 1.5 mg/kg SC", "See -More Drug Info-", "See -More Drug Info-", "Alt. Route: 0.5 mg/kg SC", "See -More Drug Info-", "See -More Drug Info-", "See -More Drug Info-", "See -More Drug Info-", "See -More Drug Info-", "See -More Drug Info-", "See -More Drug Info-", "Propulsid stimulates the release of the hormone acetylcholine at key nerve endings along the *lower* GI tract. It restores rhythmic contractions in the intestines, so food moves out of the stomach at a faster rate. It is more specific and targeted in its effects than metoclopramide. Drug availability is restricted. Serious/fatal cardiac arrhythmias including ventricular tachycardia, ventricular fibrillation, torsades de pointes, and QT prolongation have been reported in patients taking Propulsid (cisapride), especially in combination with with other drugs that inhibit cytochrome P450 3A4 enzymes.", "Administer 2-3 hours prior to medications.", "Shock volume of fluids = 44 mL/kg/hour", "Do not use if obstruction - may cause rupture! Metoclopramide stimulates movement of the *upper* GI tract through a direct effect on dopamine receptors in the brain. It reduces nausea, slows/soothes the stomach and intestine, and improves the absorption of other oral medications.", "See -More Drug Info-", "See -More Drug Info-", "1 tsp Viokase + 3 tbsp yogurt; let stand 15 min, then give.", "See -More Drug Info-", "See -More Drug Info-", "Dilute to 1O mg/mL with saline.", "See -More Drug Info-", "Use corticosteroids infrequently & with caution.", "Agranulocytosis, shock. Banned in some countries.", "See -More Drug Info-", "See -More Drug Info-", "See -More Drug Info-", "Use corticosteroids infrequently & with caution.", "See -More Drug Info-", "Use corticosteroids infrequently & with caution.", "Treat for 7 days.", "See -More Drug Info-" ) // Check for missing fields if (form.weight.value == null || form.weight.value.length == 0) { alert ("\nEnter the rabbit\'s weight."); Correct = false; } if (form.drug.selectedIndex == null || form.drug.selectedIndex == 0 || form.drug.selectedIndex == 28 || form.drug.selectedIndex == 30 || form.drug.selectedIndex == 49 || form.drug.selectedIndex == 53 || form.drug.selectedIndex == 75 || form.drug.selectedIndex == 89 || form.drug.selectedIndex == 94 || form.drug.selectedIndex == 100 || form.drug.selectedIndex == 108) { alert ("\nYou must select a drug!"); Correct = false; } // Check that only numbers are in the weight fields else { // Holds the rabbit's weight var TestWeight; // Parse the weight value and store it as a variable TestWeight = parseFloat(form.weight.value); // Check to see that TestWeight is a number if (isNaN (TestWeight)) { alert("\nMake sure to enter the rabbit\'s weight\nas a number."); Correct = false; form.weight.value=""; } // Check for a realistic rabbit weight. if((TestWeight <= 0) || (TestWeight > 20 && form.units[0].checked) || (TestWeight > 44 && form.units[1].checked) ) { alert("\nEnter a REALISTIC weight for a rabbit."); Correct = false; form.weight.value=""; } } // If all input is correct, calculate the dosage. if (Correct) { // Holds the calculated dose in mg. var RX, RX1, RX2; form.range.value = drugRange[form.drug.selectedIndex]; form.frequency.value = drugFreq [form.drug.selectedIndex]; form.route.value = drugRoute[form.drug.selectedIndex]; form.warning.value = drugWarn [form.drug.selectedIndex]; // Combination Doses: if (form.drug.selectedIndex == 55) { RX1 = .75 * TestWeight; RX2 = 32.5 * TestWeight; if (form.units[1].checked) { RX1 = RX1 * .4535924; RX2 = RX2 * .4535924; } form.dose.value = RX1 + " mg acepromazine + " + RX2 + " mg ketamine"; } else if (form.drug.selectedIndex == 62) { RX1 = 30. * TestWeight; RX2 = 3. * TestWeight; if (form.units[1].checked) { RX1 = RX1 * .4535924; RX2 = RX2 * .4535924; } form.dose.value = RX1 + " mg ketamine + " + RX2 + " mg diazepam"; } else if (form.drug.selectedIndex == 63) { RX1 = 30. * TestWeight; RX2 = 4. * TestWeight; if (form.units[1].checked) { RX1 = RX1 * .4535924; RX2 = RX2 * .4535924; } form.dose.value = RX1 + " mg ketamine + " + RX2 + " mg xylazine"; } // Weight Invariant Doses: else if (form.drug.selectedIndex == 9 || form.drug.selectedIndex == 12 || form.drug.selectedIndex == 46 || form.drug.selectedIndex == 50 || form.drug.selectedIndex == 51 || form.drug.selectedIndex == 52 || form.drug.selectedIndex == 102 || form.drug.selectedIndex == 107 || form.drug.selectedIndex == 116 || form.drug.selectedIndex == 118 || form.drug.selectedIndex == 120) { RX = drugDosage[form.drug.selectedIndex]; form.dose.value = RX + drugUnits[form.drug.selectedIndex]; } // Calculated Doses: else { RX = drugDosage[form.drug.selectedIndex] * TestWeight; // Pounds --> kilograms units conversion. if (form.units[1].checked) { RX = RX * .4535924; } // Fluids: if (form.drug.selectedIndex == 103) { RX = RX + 70.; } // Append proper units. if (RX >= .001) { form.dose.value = RX + drugUnits[form.drug.selectedIndex]; } else { form.dose.value = ""; } } } } // -->