 |
|
| Clint W. Abner, Ph.D. |
|
| Education |
| B.S. in Microbiology with a minor in Chemistry, University of Arkansas |
| Ph.D. in Biochemistry and Molecular Biology, University of Florida |
|
| Publications |
Vallur, A. C., Feller, J. A., Abner, C. W., Tran, R. K. and Bloom, L. B. (2002) Effects of hydrogen bonding within
a damaged base pair on the activity of wild type and DNA-intercalating mutants of human alkyladenine DNA glycosylase.
J. Biol. Chem. 277, 31673-31678.
|
Abner, C. W., Lau, A. Y., Ellenberger, T., and Bloom, L. B. (2001) Base excision and DNA binding activities of
human alkyladenine DNA glycosylase are sensitive to the base paired with a lesion.
J. Biol. Chem. 276, 13379-13387.
|
|
| Left the Bloom Lab for: |
| a postdoctoral position at St. Jude Children's Research Hospital in the laboroatory
of Peter McKinnon. |
 |
|
| Stephen G. Anderson, Ph.D. |
|
| Education |
| B.S. in Molecular Biology and Microbiology, University of Central Florida |
| Ph. D. in Medical Sciences, Biochemistry & Molecular Biology, University of Florida |
|
| Publications |
| Anderson, S.G., Williams, C.R., O'Donnell, M. and Bloom, L.B. (2007)
A function for the psi subunit in loading the Escherichia coli DNA polymerase sliding clamp.
J. Biol. Chem. 282, 7035-7045. |
|
| Left the Bloom Lab for: |
| a postdoctoral position at the University of Florida in the laboratory of
Scott Grieshaber. |
 |
|
| Brandon Ason, Ph.D. |
|
| Education |
| B.S. in Genetics, University of Georgia |
| M.S. in Chemistry & Biochemistry, Arizona State University |
| Ph.D. in Biochemistry, University of Wisconsin, Madison |
|
| Publications |
Ason, B., Handayani, R., Williams, C.R., Bertram, J.G., Hingorani, M.M, O'Donnell, M., Goodman, M.F, and Bloom, L.B.
(2003) Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA:
Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp.
J. Biol. Chem. 278, 10033-10040.
|
Ason, B., Bertram, J.G., Hingorani, M.M., Beechem, J.M., O'Donnell, M., Goodman, M.F., and Bloom, L.B.
(2000) A model for Escherichia coli DNA polymerase III holoenzyme assembly at primer/template ends:
DNA triggers a change in binding specificity of the gamma complex clamp loader. J. Biol. Chem. 275, 3006-3015.
|
|
| Left the Bloom Lab for: |
| the Ph. D. program at the University of Wisconsin, Madison, in the laboratory of William Reznikoff. |
 |
|
| Robyn L. Maher, Ph.D. |
|
| Education |
| B.S. in Biochemistry & Molecular Biology, The Pennsylvannia State University |
| Ph. D. in Medical Sciences, Biochemistry & Molecular Biology, University of Florida |
|
| Publications |
Maher, R.L. and Bloom, L.B. (2007) Pre-steady-state kinetic
characterization of the AP endonuclease activity of human AP endonuclease 1. J. Biol. Chem. 282, 30,577-30,585.
|
Maher, R.L., Vallur, A.C., Feller, J.A. and Bloom, L.B. (2006) Slow base excision by human
alkyladenine DNA glycosylase limits the rate of formation of AP sites and AP endonuclease 1 does
not stimulate base excision. DNA Repair 6, 71-81.
|
Vallur, A.C., Maher, R.L. and Bloom, L.B. (2005) The efficiency of hypoxanthine excision by
alkyladenine DNA glycosylase is altered by changes in nearest neighbor bases. DNA Repair
4, 1088-1098.
|
|
| Left the Bloom Lab for: |
| a postdoctoral position at the University of Vermont in the laboratory of Scott Morrical. |
 |
|
| Aarthy C. Vallur, Ph.D. |
|
| Education |
| B.S. in Nutrition and Dietetics, SR College, Trichy, TN, India |
| M.S. in Biochemistry and Molecular Biology, University of Madras, Chennai, TN, India |
| Ph. D. in Medical Sciences, Biochemistry & Molecular Biology, University of Florida |
|
| Publications |
Maher, R.L., Vallur, A.C., Feller, J.A. and Bloom, L.B. (2006) Slow base excision by human
alkyladenine DNA glycosylase limits the rate of formation of AP sites and AP endonuclease 1 does
not stimulate base excision. DNA Repair 6, 71-81.
|
Vallur, A.C., Maher, R.L. and Bloom, L.B. (2005) The efficiency of hypoxanthine excision by
alkyladenine DNA glycosylase is altered by changes in nearest neighbor bases. DNA Repair
4, 1088-1098.
|
Vallur, A. C., Feller, J. A., Abner, C. W., Tran, R. K. and Bloom, L. B. (2002) Effects of hydrogen bonding within
a damaged base pair on the activity of wild type and DNA-intercalating mutants of human alkyladenine DNA glycosylase.
J. Biol. Chem. 277, 31673-31678.
|
|
| Left the Bloom Lab for: |
| a postdoctoral position at the University of Washington in the laboratory of Nancy Maizels. |
 |
|
| Christopher R. Williams, Ph.D. |
|
| Education |
| B.S. in Biotechnology, William Paterson University, NJ |
| Ph. D. in Biochemistry & Molecular Biology, University of Florida |
|
| Publications |
Anderson, S.G., Williams, C.R., O'Donnell, M. and Bloom, L.B. (2007)
A function for the psi subunit in loading the Escherichia coli DNA polymerase sliding clamp.
J. Biol. Chem. 282, 7035-7045.
|
Snyder, A.K., Williams, C.R., Johnson, A., O'Donnell, M. and Bloom, L.B. (2004) Mechanism
of loading the Escherichia coli DNA polymerase III sliding clamp. II. Uncoupling the beta and DNA binding
activities of the gamma complex. J. Biol. Chem. 279, 4386-4393.
|
Williams, C.R., Snyder, A.K., Kuzmic, P., O'Donnell, M. and Bloom, L.B. (2004) Mechanism of loading
the Escherichia coli DNA polymerase III sliding clamp. I. Two distinct activities for individual ATP sites
in the gamma complex. J. Biol. Chem. 279, 4376-4385.
|
Ason, B., Handayani, R., Williams, C.R., Bertram, J.G., Hingorani, M.M, O'Donnell, M., Goodman, M.F, and Bloom, L.B.
(2003) Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA:
Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp.
J. Biol. Chem. 278, 10033-10040.
|
|
| Left the Bloom Lab for: |
| a postdoctoral position at Purdue University in the laboratory of Peixuan Guo. |
