Health Policy and Economic Research Unit British Medical Association

Levine Mason Brown

Ulrich Burkert, Norman L Allinger

Wayne Hendrickson

Wayne A. Hendrickson

Alexander McPherson

Roy McWeeny

Medicode

Gregory Petsko, Dagmar Ringe Protein Structure and Function provides a critical survey of our current understanding protein structure and function in the age of genomics. Moving from sequence to structure, and structure to function, the book also explores the link between sequence and function in a series of case studies in structural and functional genomics.

RUSSELL, Chopra

ADOBE

S.H. Barondes About one in 100 people suffer from full-blown manic depressive illness. Many more of us experience milder versions of this condition. One of these mild forms, called hypomania, may even confer adaptive advantages on the lucky sufferer, bestowing optimism, charisma and creative thinking, tempered by bouts of mild depression which keep manias in check and serve as signals to others to offer compassion and help.

The search for the genetic basis of mania and depression is at once a major medical priority (one in five people with manic depression commit suicide), and merely the latest step in an age-old quest to understand what purpose emotions serve.

Each major paradigm of mind has its own anatomy of melancholy. Samuel Barondes traces these rival models of despond, from the earliest writings of psychotherapy, through modern psychiatry's progressive integration into hospital medicine, to the gathering of evidence to suggest that there is a genetic component to the disease. This possibility in particular is complicating—if not revolutionising—our ideas of human nature, nurture and identity.

Barondes' own story of how he came to be involved in the hunt for "mood genes" is a pacy, no-punches-pulled memoir offering insights into genetics both as an exercise in pure science and as a job of work with all its attendant political, professional and ethical dilemmas. Long after the findings discussed here have been superseded, Mood Genes deserves to be treasured as a fascinating account of a life in science. —Simon Ings

W.F. Bodmer, Robin McKie

Stephen Brenner

J.I.G. Cadogan

Stephen Coffin

Hugh D. Crone

Prof Jeremy W. Dale

James Duncan Davidson

Richard Dawkins Richard Dawkins is not a shy man. Edward Larson's research shows that most scientists today are not formally religious, but Dawkins is an in-your-face atheist:

I want to persuade the reader, not just that the Darwinian world-view happens to be true, but that it is the only known theory that could, in principle, solve the mystery of our existence.

The title of this 1986 work, Dawkins's second book, refers to the Rev. William Paley's 1802 work, Natural Theology, which argued that just as finding a watch would lead you to conclude that a watchmaker must exist, the complexity of living organisms proves that a Creator exists.

Not so, says Dawkins: "All appearances to the contrary, the only watchmaker in nature is the blind forces of physics, albeit deployed in a very special way...it is the blind watchmaker".

Dawkins is a hard-core scientist: he doesn't just tell you what is so, he shows you how to find out for yourself. For this book, he wrote Biomorph, one of the first artificial life programs.

Carl Djerassi Most scientists are lucky if they can base a career on one big discovery. But as This Man's Pill reveals, Carl Djerassi, who first synthesised the birth control pill, has managed to squeeze two careers—so far—out of that feat. His memoir published on the pill's 50th birthday, is a warm and funny reflection on his work as research chemist and man of letters; with several novels and plays under his belt, Djerassi is an insightful writer far past the journeyman stage. Exploring the pill's reception and the various battles it's faced internationally, he offers his own thoughts on the subjects of medical ethics, sexuality and politics while sharing his complex life story. Reminiscent of Richard Feynman's playfully free spirit, Djerassi's voice will inspire readers interested in the confluence of science and art. —Rob Lightner

M.J. Englefield

James D. Foley, A.Van Dam

John A. Henry, Martyn Page

A.A. Hopgood

Adobe Systems Inc.

Ivar Jacobson, Grady Booch, James Rumbaugh A software process defines the steps required to create software successfully. Written by the same authors who brought you the Unified Modelling Language (UML), The Unified Software Development Process introduces a new standard for creating today's software that will certainly be useful for any software developer or manager who is acquainted with UML.

Early sections introduce four basic principles of the unified process: that software should stress use cases (which show how it interacts with users), that the process is architecture-centric and that it is iterative and incremental. The authors then apply these principles to their software process, which involves everything from gathering system requirements to analysis, design, implementation and testing. The use-case examples are excellent and include concrete examples drawn from such areas as banking and inventory control.

The authors point out the connection between UML document types (like use-cases, class diagrams and state transition diagrams) with various models used throughout the software process. They provide very short, real-world examples that illustrate how their ideas have been successfully applied. The straightforward tour of the new unified software process gets extra elaboration—along with some advice—in later chapters that further describe the author's ideas on design. With the weight of these three expert authors behind it, readers can expect The Unified Software Development Process to be an important book and one that will be valuable to any working designer or manager. —Richard Dragan

Tim King, George Reese, Randy Yarger, Hugh E. Williams Managing and Using MySQL describes the installation, administration and programming of this hugely popular open source database manager. The main focus is on using MySQL in Web applications hosted on Linux or Unix. The book is based on MySQL 3.23. It’s aimed at programmers, but database design and the SQL language are explained from scratch, so it’s also suitable for Web developers who are beginners when it comes to databases.

The scene is set with a brief history of MySQL, explaining its position as a fast and generally free alternative to the fuller-featured commercial heavyweights like Oracle or DB2. Next comes an introduction to SQL, followed by three chapters on administration, covering configuration, data recovery, tuning, security and user management. There's a brief look at database design too. That accounts for around one third of the book. The rest is about programming with chapters on using MySQL from Perl, Python, PHP and Java, and a look at how to extend MySQL with user-defined functions written in C. The last part of the book is a reference section, covering SQL syntax and functions, along with the MySQL API in PHP, C, and Python.

This is an excellent book for getting started with MySQL as well as a convenient reference. It has a broad scope, which means it does not go deeply into the various topics. For example, those using PHP might be better off with a more specialist title like Web Database Applications with PHP and MySQL. On the other hand, Managing and Using MySQL is ideal for a general and highly accessible overview of what MySQL can do.—Tim Anderson

P.F. Leadley

Richard C. Lewontin Leading geneticist Richard Lewontin's It Ain't Necessarily So: The Dream of the Human Genome and Other Illusions consists of a collection of essays written over a period of 17 years for the New York Review of Books dealing with various aspects of biology and human biology in particular. Lewontin discusses Darwin, Mendel, natural selection, heredity, and the current state of play in modern genetics while damning what he sees as widespread biological determinism from the sociobiology of the recent past to the current "vulgar Darwinism" of the present. IQ testing, and gene therapy, evolutionary psychology, and feminist notions of gendered knowledge all come under fire.

The title essay "The Dream of the Human Genome" is a review of nine major books up to 1992 and an attack on the Genomic "grail knights" that, in Lewontin's view, represent administrative and financial organisations rather than a promising research program. On this view the sequence of the human genome is not a trail leading to the Holy Grail, it will not reveal what it is to be human nor change our philosophical view of ourselves, nor, perhaps, will it translate into therapeutic techniques. Lewontin wants to arm the general public against the seductiveness of biological explanations which "often seem to smell of material reality even when they are equally speculative".

Lewontin is a working scientist who knows the importance of philosophy. He is also a superb essayist and this collection is a waffle-free, informative, unpretentious eye-opener. The book leaves you sceptical about the integrity of scientists and more circumspect about claims concerning the universal explanatory reach of biology. —Larry Brown

Tom Lichty

Niccolo Machiavelli

Dinesh Mehta

Dinesh Mehta

Michael J. Neal

Tom Negrino, Dori Smith

Clive Page

M.F. Perutz

David Pogue Widely esteemed Mac authority David Pogue weighs in on the latest offering from Cupertino with Mac OS X: The Missing Manual. It's a fact-packed romp through the operating system and the extras that come with it, made resoundingly more readable by the depth of Pogue's knowledge, his familiarity with Mac history, and his eagerness to engage novices as members of the Mac user community. Unlike most books about Mac OS X, this one explores its Unix-like underpinnings (the Apple implementation is called Darwin) pretty thoroughly. However, on the logic that if you wanted to use Unix, you would, Pogue emphasises the traditional, graphical Mac interface over the Terminal window.

Pogue, who's written about Macs for years writes about Macs at the user level with clarity. He's also quite good at dealing with the numerous options and variations that apply to Mac procedures, and makes very good use of sidebars for clarifying details. In a section on printing, for example, Pogue explains why there's no longer an option to turn off background printing (true multitasking has rendered the option obsolete). There's also good coverage of the online iTools, tailored to people unfamiliar with integrating remote resources into their personal computing environments. —David Wall

Topics covered: Apple Mac OS X for people who will use the operating system, either on a standalone computer with Internet access or on a computer that is part of a home or organisational network. Running applications (in Classic mode as well as in native Mac OS X mode), printing, networking, multimedia, security (including Keychain), and utilities are all covered.

William H. Press, Saul A. Teukolsky, William T. Vetterling, Brian P. Flannery

Matt Ridley.

Arnold Robins Unix in a Nutshell is the standard desktop reference, without question (Manpages come in a close second). With clean layout and superior command tables available at a glance, O'Reilly's third edition of Nutshell is an essential to own.

Like a dictionary, Unix in a Nutshell helps you find what you need, even if you're not exactly sure what it is you're looking for (or how to spell it!) With that in mind, this book is for intermediate to advanced users only—those new to the Unix operating system would be better off with Learning the Unix Operating System or Unix: Visual Quickstart Guide.

The last full revision of the book was in 1992, and the new edition covers Solaris 7, as well as newer versions of shells (ksh, in particular), RCS and GNU emacs. Topping off at over 500 pages, Unix in a Nutshell contains—literally—everything you could want to know about the various commands, shells and functions. Fifty new commands have been added to the already sizable lists, and even the most seasoned user is likely to find a timesaving command not previously known. —Jennifer Buckendorff

New Scientist What time is it at the North Pole? Should you pickle your conkers? Why does my aubergine look like Elvis? This title compiles readers' answers to the questions in the 'Last Word' column of 'New Scientist', one of the world's best-selling science weeklies.

John Maynard Smith

James Clare Speakman

Jeffrey Steingarten THE MAN WHO ATE EVERYTHING was the winner of The Guild of Food Writers Book of the Year and was a bestseller in the UK and US.

Henry Sticker

Rajshekhar Sunderraman

Graham J.G. Upton, Ian Cook

Nancy Walsh

Robert A Weinberg "Cancer wreaks havoc in almost every part of the human body"—Robert Weinberg's opening remark is a chilling reminder of the pervasiveness of an all-too- familiar disease. Cancer touches most families and if you have ever wondered why, despite so much time, effort and money, it has proved such a seemingly intractable problem, then read One Renegade Cell, Robert Weinberg's masterful explanation. As Director of the Oncology Research Laboratory at the Whitehead Institute and Professor of Biology at M.I.T. in Cambridge, Massachusetts, Weinberg has been at the forefront of cancer research for well over a decade.

Unlike most diseases, cancerous tumours are not foreign invaders but "take on the appearance of alien life forms, invaders that enter the body through stealth and begin their programs of destruction from within." But as Weinberg shows these are deceptive appearances. And since he is foremost a scientist, he finds the truth "subtle and endlessly interesting" and manages to convey this fascination for something that most of us dread—cancer. Much of the present increase in cancer is due to increased longevity because "given enough time, cancer will strike every human body".

By telling the story of the historical discovery of cancer, Weinberg is able to introduce gradually the intricacies and complications of the genes and proteins involved (oncogenes, tumour suppressor genes etc) for the general reader. He characterises cancer cells as renegade because unlike normal body cells, they "disregard the needs of the community of cells", they are "selfish and unsociable", only interested in "their own proliferative advantage." By comparison, normal cells hold down cell numbers by "inducing them to commit suicide" (apoptosis).

The understanding of cancer has been developed enormously over the last few decades by Weinberg and the worldwide community of researchers. As Weinberg eloquently shows, cancer research and its related disciplines "have moved from substantial ignorance to deep insight."

The book is published as one of a series of Science Masters, of which a dozen have been published. They are designed to help the popularisation of science and are written by established and well-known scientists. The authors, such as Richard Dawkins (River out of Eden), Richard Leakey (The Origin of Humankind) and Lynn Margulis (The Symbiotic Planet) are also known for their ability to communicate science to a general readership. —Douglas Palmer

D.G. Wells

L. Wolpert, Alison Richards

Lewis Wolpert Lewis Wolpert had a severe depressive episode, and despite a happy marriage and successful scientific career, he could think only of suicide. When he recovered, he wrote this book, an investigation into the causes and treatments of this disease. This edition features an introduction, in which Lewis Wolpert discusses his struggle with depression.

Robert Youngson

William Findlay

James D. Watson

Valerie Joyce Calderbank

Andrew Streitwieser, Clayton H. Heathcock

Mccabe

David Michael Hirst

Richard Dawkins Few scientific theories have been as influential or controversial in the past few centuries as Darwin's thoughts on natural selection; even now, laymen and scientists find fault with Darwin's argument. Richard Dawkins, the chair of the communication of science at Oxford University, has delivered a well-researched book supporting and supplementing Darwin's theories. Although not a work of Darwinian proportions, Climbing Mount Improbable is an advancement of those theories for scientists and general readers alike.

John Martin This is the authoritative prescribing resource of choice for healthcare professionals. Compiled with the advice of clinical experts, this essential reference provides up-to-date guidance on prescribing, dispensing and administering medicines. It includes the BNF details medicines prescribed in the UK, with special reference to their uses, cautions, contraindications, side-effects, dosage and relative costs. Updated in print every six months, the BNF reflects current best practice as well as legal and professional guidelines relating to the use of medicines.The BNF is also available online as part of Medicines Complete, on PDA and on also CD-ROM for intranets.

N.N. Greenwood

John F. Koegel Buford

Gunnar Von Heijne

Thomas E Creighton

Adam Hart-Davis

Peter Wainright

Natalie Zee, Susan Harris

Richard Dawkins

Usama M Fayyad

P.C.E. Moody

Annette M. Doherty

John C Kendrew

Nicholas C. Price, Lewis Stevens

James Olson

Duncan J. Shaw

James A. Bristol

B.A. Marples

Harvey M. Deitel, Paul J. Deitel, B. DuWaldt, L. K. Trees

Elaine Rich, Kevin Knight

C. Ritchie

P.A.H. Wyatt

Jenny Uglow Among the group of Midlands amateur experimenters who formed the Lunar Society and kick-started the Industrial Revolution, were Matthew Boulton, Josiah Wedgewood, James Watt and Erasmus Darwin. This account uncovers the friendships, political passions and love of knowledge that drove these men.

Eric S. Raymond This volume contains the essays, originally published online, that led to Netscape's decision to release their browser as open source, and helped Linux to rock the world of commercial software.

Erik T. Ray This new edition of the bestselling Learning XML provides web developers with a concise but grounded understanding of XML (the Extensible Markup Language) and its potential—not just a whirlwind tour of XML. Learning XML illustrates the core XML concepts and language syntax, in addition to important related tools such as the CSS and XSL styling languages and the XLink and XPointer specifications for creating rich link structures. It includes information about three schema languages for validation: W3C Schema, Schematron, and RELAX-NG, which are gaining widespread support from people who need to validate documents but aren't satisfied with DTDs. Also new in this edition is a chapter on XSL-FO, a powerful formatting language for XML.

Richard Headstrom

Fran Hawthorne

Per Kroll, Philippe Kruchten

Tom Cargill

P.G. Ashmore

D.S. Urch

Stephen Wolfram

Edward Cartmell

James A. Bristol, David W. Robertson, Annette M. Doherty, Jacob J. Plattner, William K. Hagmann, Winnie W. Wong, George L. Trainor

Ethan Cerami This text offers programmers both an introduction and reference to XML Web services. It explains the foundations of these distributed services, demonstrates quick ways to create services with open-source Java tools, and explores four key emerging technologies: XML-RPC, SOAP, UDDI, and WSDL.

Max Perutz This collection of essays from Nobel Laureate Max Perutz explores a wide range of scientific and personal topics with insight and lucidity. It includes lively anecdotes about key figures in 20th-century science.

Steven Pinker Steven Pinker has a very good ear; you know it instantly from his prose: elegant, accessible and very witty indeed. In Words and Rules, Pinker picks apart our language to reveal pro found truths about how we think.

Do we deduce rules from the world around us and behave rationally? Or do we free-associate, discovering the world through experience and creative analogy? The obvious answer is "both". But proof of the obvious answer has long eluded philosophers of mind. Pinker, though, believes he has found it—in the English past tense.

English verbs come in two flavours. Regular verbs have past tenses that look like the present-tense verb with "-ed" on the end—today I walk, yesterday I walked, etc. The second kind of English verb is irregular. Irregular past tenses follow no rules—today I buy, but yesterday I bought; today I hold, yesterday I held.

The way children distinguish between these different sorts of verbs as they learn to talk suggests they learn both by rule and by association. Proving this is Pinker's task—and it's a bravura performance.

It takes nothing away from that other recent lit-hit, Bill Bryson's Mother Tongue, to say that Pinker's book achieves an altogether deeper level of profundity. It says much for Pinker that in doing so, he can still match Bryson for wit and readability. —Simon Ings

Francis A. Carey, Richard J. Sundberg Since its original appearance in 1977, Advanced Organic Chemistry has found wide use as a text providing broad coverage of the structure, reactivity and synthesis of organic compounds. The Fourth Edition provides updated material but continues the essential elements of the previous edition. The material in Part A is organized on the basis of fundamental structural topics such as structure, stereochemistry, conformation and aromaticity and basic mechanistic types, including nucleophilic substitution, addition reactions, carbonyl chemistry, aromatic substitution and free radical reactions. The material in Part B is organized on the basis of reaction type with emphasis on reactions of importance in laboratory synthesis. As in the earlier editions, the text contains extensive references to both the primary and review literature and provides examples of data and reactions that illustrate and document the generalizations. While the text assumes completion of an introductory course in organic chemistry, it reviews the fundamental concepts for each topic that is discussed.
The Fourth Edition updates certain topics that have advanced rapidly in the decade since the Third Edition was published, including computational chemistry, structural manifestations of aromaticity, enantioselective reactions and lanthanide catalysis.
The two parts stand alone, although there is considerable cross-referencing. Part A emphasizes quantitative and qualitative description of structural effects on reactivity and mechanism. Part B emphasizes the most general and useful synthetic reactions. The focus is on the core of organic chemistry, but the information provided forms the foundation for future study and research in medicinal and pharmaceutical chemistry, biological chemistry and physical properties of organic compounds.

The New Revised 5th Edition will be available shortly. For details, click on the link in the right-hand column.

Marcia Angell

Henry Plotkin

Leon A. Wortman, Thomas O. Sidebottom

Susan Blackmore Humans have the ability to imitate and copy behaviours, or memes, from one another. This is an investigation of whether genes and memes can lead to discoveries about the nature of the inner self and whether the inner self is only an illusion created by the memes for the sake of replication.

RE Geis, I Dickerson

Brian W. Kernighan, P.J. Plauger

Rona M. MacKie

Edward O. Wilson Our world is far richer than previously conceived, yet so ravaged by human activity that half its species could be gone by the end of the 21st century. E.O. Wilson describes exactly which treasures of the natural world we are about to lose forever and what we can do right now to save them.

F.Albert Cotton, Sir Geoffrey Wilkinson

Cynthia Gibas, Per Jambeck The application of computational and analytical methods to biological problems is a rapidly evolving scientific discipline. This book is designed to help any biologist develop a structured approach to data, as well as provide the tools they'll need to analyze it.

John Haigh What are the odds against winning the Lottery, making money in a casino, or backing the right horse? Every day, people make judgements on these matters, yet many of us are ignorant of how probability works. This exploration reveals traps and fallacies in the field, describing and analysing a variety of situations where chance plays a role

John Emsley What is it in chocolate that makes us feel good when we eat it? What's the molecule that turns men on? What's the secret of Coca-Cola? In this book, the author takes us on a guided tour through a rogue's gallery of molecules, some harmful, some pleasant, showing how they affect our lives.

E CARTMELL & FOWLES.G.W.A

Karl Marx, David McLellan

Peter Sykes

James A. Bristol, William K. Hagmann, Michael C. Venuti

Steven Johnson It is fast becoming clear that our lives revolve around the powers of emergence. Order arrives from the bottom-up, not top-down. This work looks at the cities we inhabit, the media frenzies we suffer and the games we play, showing how individual actions without central planning often create a wonderfully adaptive communal intelligence.

Mark Lutz Portable, powerful, and a breeze to use, Python is ideal for both standalone programs and scripting applications. With this hands-on book, you can master the fundamentals of the core Python language quickly and efficiently, whether you're new to programming or just new to Python. Once you finish, you will know enough about the language to use it in any application domain you choose. Learning Python is based on material from author Mark Lutz's popular training courses, which he's taught over the past decade. Each chapter is a self-contained lesson that helps you thoroughly understand a key component of Python before you continue. Along with plenty of annotated examples, illustrations, and chapter summaries, every chapter also contains Brain Builder, a unique section with practical exercises and review quizzes that let you practice new skills and test your understanding as you go. This book covers: Types and Operations — Python's major built-in object types in depth: numbers, lists, dictionaries, and more Statements and Syntax — the code you type to create and process objects in Python, along with Python's general syntax model Functions — Python's basic procedural tool for structuring and reusing code Modules — packages of statements, functions, and other tools organized into larger components Classes and OOP — Python's optional object-oriented programming tool for structuring code for customization and reuse Exceptions and Tools — exception handling model and statements, plus a look at development tools for writing larger programs. Learning Python gives you a deep and complete understanding of the language that will help you comprehend any application-level examples of Python that you later encounter. If you're ready to discover what Google and YouTube see in Python, this book is the best way to get started.

Andreas D. Baxevanis, B. F. Francis Ouellette

Nassim Nicholas Taleb What have the invention of the wheel, Pompeii, the Wall Street Crash, Harry Potter and the internet got in common? Why are all forecasters con-artists? And, what can Catherine the Great's lovers tell us about probability? This book shows us how to stop trying to predict everything and take advantage of uncertainty.

Dr. Guy Bunker

Linus Pauling

James Watson The story of the most significant biological breakthrough of the century - the discovery of the structure of DNA.

Alice M. Sapienza, Diana Stork

J. Drews

Trevor Stone, L. Gail Darlington From barbiturates to Bacardi Breezers, from antibiotics to Earl Grey tea, human beings depend on drugs to an extraordinary degree: whether it's cancer, boredom, frigidity or shyness, we snort, drink, pop, smoke and inject to cure or alleviate the ills of existence. Without drugs life would be unimaginably different—and unimaginably painful.

Given this universal drug culture, a book which attempts to explain the whats, whys and wherefores of the thousands of drugs we use can only be timely and helpful. But professional physicians and pharmacologists Stone and Darlington have also striven to make their text stimulating and enjoyable—and to a large extent they have succeeded.

The format is simple. It takes the reader through the pharmacopoeia illness by illness, with attendant, rigorously scientific, but never obscure explanations as to the provenance, virtues and side-effects of the relevant medication. The historical and ancillary material deftly woven into the text is sometimes poignant, sometimes hilarious. Dominant male chimps enjoy a natural 'mental' Prozac; Queen Victoria's doctor thought epilepsy was caused by masturbation; eighty years ago kits of morphine and syringes could be bought at stores as 'a useful present'. Between these fascinating asides the authors discuss issues like schizophrenia, heart disease and depression—all of which have seen revolutions in the pharmacological treatment available in the last few years.

After several chapters on recreational drugs, toxicology, and "aphrodisiacs", the book culminates with a short but perceptive essay on the development and marketing of new drugs—such as tolcapone. Tolcapone seems to offer exciting possibilities in the treatment of Parkinsonism, but it also causes, in some, liver damage. The book's clear-headed analysis of this complex dilemma exemplifies why Pills, Potions and Poisons will be of value to anyone who has ever taken drugs. Which, of course, means everyone.—Sean Thomas

P.C. Turner, A.G. McLennan, A.D. Bates, M. R. H. White

Annette M. Doherty

Rita Carter The brain has been the last "terra incognita" of the body for medical exploration, largely because its matter is so different from that of the rest of the body. In 1986 the eminent evolutionary biologist John Maynard Smith identified the problem of how the brain works as one of the two outstanding problems in biology (along with how a simple egg develops into a complex adult organism). Most of us have experienced some apparently inexplicable quirk of the mind, such as selective memory loss. Without obvious "hard wiring", anatomical "labels" or other guiding features, medical scientists have struggled to identify its parts, their functions and connections to the mind. Not that this has stopped curiosity; there is anthropological evidence dating back some thousands of years for crude but sometimes successful attempts to open the skull and get at the brain.

Rita Carter is an award-winning medical writer. (Medical Journalists' Association prize for outstanding contribution). In Mapping the Mind she explores the landscape of the brain and its connections with the mind. We should all be enthralled by this adventure for "it is giving us greater understanding about one of the oldest and most fundamental of mysteries—the relationship between the brain and mind". Carter introduces the subject with the historical background of anatomical discoveries and emerging theories of brain/mind connections. The famous tragic story of the 19th-century American railway worker, Phineas Gage, is here. An iron rod blasted through poor Phineas's skull. It entered below his left eye and exited through his skull roof, removing a large chunk of his forebrain. Amazingly, Phineas survived but his personality was radically changed, as was reported by his doctor, John Harlow.

In this fascinating and well-illustrated book, Rita Carter shows just how far we have travelled in our understanding since the mid-19th century world of Dr Harlow and gives a sense of how far we still have to travel. As she says: "The world within our heads is more marvellous than anything we can dream up". The last few decades have seen a revolution in non-invasive brain mapping thanks to the scientific miracles of Magnetic Resonance Imaging and associated technologies. It is now possible to see which part of the brain responds to specific stimulation in real time. As Rita Carter says: "The challenge of mapping this world...is currently engaging some of the finest scientists in the world". Excellent design and imagery, plus vignettes from famous scientists such as Francis Crick, a bibliography and an index make this a very useful book as well as a good read. —Douglas Palmer

John N. Abelson, Melvin I. Simon, Russell F. Doolittle

John Emsley What is the most common element in the universe? Can you name the noble gases? Everything we see around us is made of chemical elements, but most of us know little about them. Penned by award-winning science writer John Emsley, Nature's Building Blocks explains the what, why and wherefore of the chemical elements. Arranged alphabetically, from Actinium to Zirconium, it is a complete guide to all 115 of those that are currently known, with more extensive coverage of those elements we encounter in our everyday life. The entry on each element reveals where it came from, what role it may have in the human body, and the foods that contain it. There are also sections on its discovery, its part in human health or illness, the uses and misuses to which it is put, and its environmental role. Readers discover that the Earth consists of around 90 elements, some of which are abundant, such as the silicon and oxygen of rocks and soils, while some are so rare that they make gold seem cheap. Our own bodies contain about 30 elements, some in abundance, some in trace amounts; some vital to our health, and some that are positively harmful. A list of the main scientific data, and outline properties, are given for every element and each section ends with an "Element of Surprise," which highlights some unexpected way in which each element influences our everyday life. Both a reliable reference source and a high browsable account of the elements, Nature's Building Blocks offers a pleasurable tour of the very essence of our material world.

P.M. Lydyard, A. Whelan, M. Fanger

Will Iverson

Charles Tanford, Jacqueline Reynolds This history of protein science involves heroes from the past, working mostly alone or in small groups, usually with little support from formal research groups. It is also a story that embraces a number of historically important scientific controversies.

David W. Robertson, Jacob J. Plattner, William K. Hagmann, Winnie W. Wong, George L. Trainor, James A. Bristol

Lawrence Hunter

Patrick Niemeyer, Jonathan Knudsen Version 5.0 of the Java 2 Standard Edition SDK is the most important upgrade since Java first appeared a decade ago. With Java 5.0, you'll not only find substantial changes in the platform, but to the language itself-something that developers of Java took five years to complete. The main goal of Java 5.0 is to make it easier for you to develop safe, powerful code, but none of these improvements makes Java any easier to learn, even if you've programmed with Java for years. And that means our bestselling hands-on tutorial takes on even greater significance.

Learning Java is the most widely sought introduction to the programming language that's changed the way we think about computing. Our updated third edition takes an objective, no-nonsense approach to the new features in Java 5.0, some of which are drastically different from the way things were done in any previous versions. The most essential change is the addition of "generics", a feature that allows developers to write, test, and deploy code once, and then reuse the code again and again for different data types. The beauty of generics is that more problems will be caught during development, and Learning Java will show you exactly how it's done.

Java 5.0 also adds more than 1,000 new classes to the Java library. That means 1,000 new things you can do without having to program it in yourself. That's a huge change. With our book's practical examples, you'll come up to speed quickly on this and other new features such as loops and threads. The new edition also includes an introduction to Eclipse, the open source IDE that is growing in popularity.

Learning Java, 3rd Edition addresses all of the important uses of Java, such as web applications, servlets, and XML that are increasingly driving enterprise applications.

Edward O. Wilson Argues for the fundamental unity of all knowledge and the need to search for 'consilience': the composition of the principles governing every branch of learning. The author shows how our rise in intellectual mastery is rooted in an ancient Greek concept at its zenith during the Enlightenment.

E.L.V. Harris, S. Angal

G.E. Schulz, R.H. Schirmer

DM ADAMS

William Strunk Jr., E. B. White This style manual offers practical advice on improving writing skills. This 'little' book can help students communicate more effectively, showing them how to enliven their sentences, put statements in the positive form and write in a clear and simple style.

J.B.C. Findlay, Michael S. Geisow

Steven Pinker Why do memories fade? Why do we lose our tempers? Why do fools fall in love? This work explores the nature and history of the human mind. It looks at the computations and evolutions, and then considers how the mind lets us see, think, feel, interact, and pursue higher callings like art, religion and philosophy.

Myers.C.S.

Richard Niemiec

Jonathan Gennick For programmers and database administrators who use SQL in their day-to-day work, this popular pocket guide is the ideal on-the-job reference. It uses numerous examples to address the language's complexity, and covers key aspects of SQL used in Oracle, DB2, SQL Server, MySQL, and PostgreSQL.

Joseph J. Villafranca

Samuel Goldberg

Chris Anderson

J.G. Cuninghame

Arthur M. Lesk

William W. Porterfield

Minoru Kanehisa

W G Richards

Andrew S. Robson, David Bawden, Alan Judd

Merck

Jane K. Setlow

John N. Abelson, Melvin I. Simon, Russell F. Doolittle

Tak W. Mak

W.J. Greenlee, William K. Hagmann, Jacob J. Plattner, David W. Robertson, George L. Trainor, Winnie W. Wong, Annette M. Doherty

Robert E. Maizell

James Le Fanu A fascinating survey of the key moments of post-war medical discovery Concludes with a genuinely original commentary on the state of medicine today

JHL Playfair, Benjamin Chain

K Muller

R. Nesse, George Williams

Cynthia Robbins-Roth

Des Higgins, Willie Taylor

Larry Wall, Tom Christiansen, Jon Orwant This text provides an introduction to the Perl programming language and its culture. This third edition has been expanded to cover Version 5.6 of Perl. New topics include threading, the compiler, and Unicode.

Christopher Chatfield, A.J. Collins

Gale Rhodes

Rock Brynner, Trent D. Stephens

Andrew J. Davison, Richard M. Elliott

M. J. Bishop, C.J. Rawlings

John Seely Brown, Paul Duguid Argues that the gap between digerati hype and end-user gloom is largely due to the 'tunnel vision' that information-driven technologies breed. This book explains how many of the tools, jobs, and organizations seemingly targeted for future extinction in fact provide useful social resources that people will fight to keep.

Frederick P. Brooks Jr. Presenting the 20th anniversary and first revised edition of a collection of essays on the management of computer programming projects, this work is an updated and enhanced re-release of the 'Brooks classic'. With the addition of 3 essays assessing the status of software project management, the authors 'No Silver Bullet', is also included.

P.B. Medawar

A ; Marwick, D H Balfour

Mark Buchanan

Prof Nick Lemoine

Jenny P. Glusker, Kenneth N. Trueblood

William T. Vetterling, Saul A. Teukolsky, William H. Press, Brian P. Flannery

Gavin Whittaker, Andy Mount, Matthew Heal

Chuck Musciano, Bill Kennedy Puts what you need to know about HTML and XHTML at your fingertips. This work shows you how to: Use style sheets to control your document's appearance; Work with programmatically generated HTML; Create tables, both simple and complex; Design and build interactive forms and dynamic documents; Insert images, sound files, video, Java applets, and more

Graham Patrick

Soraya Dhillon, Andrew Kostrzewski

Ivan Roitt, Peter Delves

T.M.R. Ellis, Ivor R. Phillips, Thomas M. Lahey This complete tutorial by three authors who contributed to the development of the FORTRAN 90 standard places a special emphasis on science and engineering applications. Building on the lead author'ssuccessful work, FORTRAN 77 Programming, the book provides a complete explanation of the new features of FORTRAN 90.

Edward R. Tufte

Jim Cassidy, Donald Bissett, Roy A.J. Spence

Ralph A. Bradshaw, Mary Purton

Annette M. Doherty

Kevin Kelly

Graham Patrick 'Instant Notes in Medicinal Chemistry' provides concise yet comprehensive coverage for undergraduates studying medicinal chemistry as part of a science, pharmacy or medical course.

Athel Cornish-Bowden

Anne Mason

Peter Morville, Louis Rosenfeld Shows information architects, designers, and web site developers how to build large-scale and maintainable web sites that are easy to navigate. This book discusses blueprints, wireframes and the role of diagrams in the design phase. It addresses emerging technologies while maintaining its focus on fundamentals.

William H. Press, Brian P. Flannery, Saul A. Teukolsky, William T. Vetterling

Stephen Wolfram Physics and computer science genius Stephen Wolfram, sets his sights on a daunting goal: understanding the universe. A New Kind of Science is a gorgeous, 1,280-page tome more than a decade in the making. With patience, insight, and self-confidence to spare, Wolfram outlines a fundamental new way of modelling complex systems.

On the frontier of complexity science since he was a boy, Wolfram is a champion of cellular automata—256 "programs" governed by simple non-mathematical rules. He points out that even the most complex equations fail to accurately model biological systems, but the simplest cellular automata can produce results straight out of nature—tree branches, stream eddies, and leopard spots, for instance. The graphics in A New Kind of Science show striking resemblance to the patterns we see in nature every day.

Wolfram wrote the book in a distinct style meant to make it easy to read, even for non-techies; a basic familiarity with logic is helpful but not essential. Readers will find themselves swept away by the elegant simplicity of Wolfram's ideas and the accidental artistry of the cellular automaton models. Whether or not Wolfram's revolution ultimately gives us the keys to the universe, his new science is absolutely awe-inspiring. —Therese Littleton

Stephen Few Teaches you the visual design skills you need to create dashboards that communicate clearly, rapidly, and compellingly. This book explains how to: avoid the thirteen mistakes common to dashboard design; provide viewers with the information they need quickly and clearly; and create an aesthetically pleasing viewing experience.

Jack Salway

Toby Segaran Demonstrates how you can build Web 2.0 applications to mine the enormous amount of data created by people on the Internet. This book explains how to draw conclusions about user experience, marketing, personal tastes, and human behavior in general - from information collected every day.

T.J. Franklin, George Alan Snow

Erik T. Ray This edition provides Web developers with a concise but grounded understanding of XML and its potential. The author explains the important and relevant XML technologies and their capabilities clearly and succinctly with plenty of real-life projects and useful examples.

Randal Schwartz, Tom Phoenix, brian d foy Learning Perl, popularly known as "the Llama," is the book most programmers rely on to get started with Perl. The bestselling Perl tutorial since it was first published in 1993, this new fifth edition covers recent changes to the language up to Perl 5.10.

This book reflects the combined experience of its authors, who have taught Perl at Stonehenge Consulting since 1991. Years of classroom testing and experience helped shape the book's pace and scope, and this edition is packed with exercises that let you practice the concepts while you follow the text. Topics include:

Perl data & variable typesSubroutinesFile operationsRegular expressionsString manipulationLists & sortingProcess managementSmart matchingUsing third party modules

Perl is the language for people who want to get work done. Originally targeted to sysadmins for heavy-duty text processing, Perl is now a full-featured programming language suitable for almost any task on almost any platform-from short fixes on the command line to web applications, bioinformatics, finance, and much more. Other books may teach you to program in Perl, but this book will turn you into a Perl programmer.

John L. LaMattina Answers the questions about the process and costs of pharmaceutical R and D in a compelling narrative focused on the discovery and development of important fresh medicines. This book offers an insider's account of the pharmaceutical industry drug discovery process, the high stakes - both economic and scientific - of developing drugs.

Arthur M. Lesk Written in a clear and engaging style, and profusely illustrated with superb computer graphics, Introduction to Protein Architecture is a textbook for second and third year undergraduate students and beginning post-graduate students, and will be of interest to all biological and medical scientists whose work touches on proteins.

The structures and functions of proteins unlock the secrets inherent in genomes, including the human genome. The emphasis of this book is on protein architecture, on proteins as three-dimensional patterns. A new field, bioinformatics, has grown up around gene and protein sequences and structures. It has captured the interest of many scientists for its intellectual challenges, its potential for useful applications, and promising scope for careers. This book introduces the use of the World Wide Web in bioinformatics.

Written by one of the leaders in this field, Introduction to Protein Architecture explains the general characteristics of proteins that underlie the very great variety of folding patterns observed in nature. For specialists in structural biology, it contains the core of what they need to know. For students and workers in related disciplines, undergraduates or beginning graduate students in biology, chemistry, medicine, bioinformatics, and related fields it contains what they will be able to apply to their own work. Topics treated include: Pattern and form in protein structure; The building blocks; The relationship between amino acid sequence and protein structure; Secondary, supersecondary and tertiary structure; Classifications and hierarchies of protein folding patterns; Protein evolution; How proteins change conformation (and why).

To suit the needs of courses, each chapter includes recommended reading, lists of useful web sites, traditional exercises, and a new type of exercise called a weblem, for WEB-based probLEM.

Brian W. Kernighan, Rob Pike

Joel Griffith Hardman, Lee E. Limbird, Alfred G. Gilman The Tenth Edition also brings the field of pharmacology up-to-date in terms of critical areas such as molecular biology, new drugs, and clinical studies that have contributed to the understanding of therapeutics and their role in the management of disease. Time-tested, yet up-to-the-minute, "G & G" is truly the most current, expert, and easy-to-use drug reference available today.

Annette M. Doherty

Julia M. Goodfellow, D.S. Moss

Creighton

Ramez Elmasri, Shamkant B. Navathe

Daniel Vasella, Robert Slater

Æleen Frisch

Gerd-Rudiger Burmester, Antonio Pezzuto

R ; Loftus, P Abraham

Ernest E. Rothman, Brian Jepson, Rich Rosen Intends to serve as a bridge for Unix developers and system administrators who've been lured to Mac OS X because of its Unix roots. This book is a guide for taming the Unix side of Mac OS X.

John Mann

D.G. Rees An introductory text for students taking a first course in statistics - in fields such as engineering, business, chemistry, and biology. It presents information on modern statistical techniques such as Analysis of Variance (ANOVA), and software such as Minitab for Windows.

Leonard Richardson, Sam Ruby You've built web sites that can be used by humans. But can you also build web sites that are usable by machines? That's where the future lies, and that's what this work shows you how to do. It puts the 'Web' back into web services. It shows how you can connect to the programmable web with the technologies you already use every day.

Peter Sykes A textbook on mechanistic organic chemistry.

Randal L. Schwartz, brian d foy, Tom Phoenix

J. Andrew McCammon, Stephen C. Harvey

G. Jolles, K.R.H. Wooldridge

Annette M. Doherty

Rick Greenwald, Robert Stackowiak, Jonathan Stern Covering various aspects of the Oracle database, this illustrated book is useful for readers of different technical levels. It includes information on Oracle's features and technologies, including the product line, architecture, data structures, networking, concurrency, tuning and more.

Robert Charles Hider, David Barlow

Tamas Bartfai, Graham V. Lees

Annette M. Doherty

Peter W. Atkins, Julio de Paula

J. Mann

Ellen Siever, Stephen Figgins, Robert Love, Arnold Robbins Focusing on Linux system essentials, this title covers programming tools, system and network administration tools, the shell, editors, LILO and GRUB boot options, and highlights the most important options for using the vast number of Linux commands. It can also help you learn Linux commands for system administration and network management.

Brian W. Kernighan, Rob Pike Helping make individual programmers more effective and productive, this book contains practical advice and real-world examples in C, C++, Java, and a variety of special-purpose languages.

Lily E. Kay

Alfred V. Aho, Ravi Sethi, Jeffrey D. Ullman

Krishna Vaddi, Margaret Keller, Matthew Newton Grad Assoc Phys Dip Injection Therapy MCSP HPC Reg MMACP MIMTA

Eric S. Raymond

Laszlo Patthy

Anthony R. West An abridged version of the author's 'Solid State Chemistry and Applications' textbook, restructured to give solid state teaching courses a coherent and logical progression of subject material. The result is designed to give students a readable introduction to this growth area.

A.R. Rees, etc., M.J.E. Sternberg, R. Wetzel

Dean Leffingwell, Don Widrig

Prof Ivan Bratko This edition has been expanded to provide a greater range of applications. It book discusses natural language processing with grammar rules, planning and machine learning, and includes coverage of meta-programming, meta-interpreters and object-oriented programming in Prolog.

Soraya de Chadarevian

David W. Robertson, Annette M. Doherty, William K. Hagmann, Jacob J. Plattner, Winnie W. Wong, George L. Trainor, James A. Bristol

Jiawei Han, Micheline Kamber, Jian Pei Our ability to generate and collect data has increased. This book explores concepts and techniques for the discovery of patterns hidden in large data sets, focusing on issues relating to their feasibility, usefulness, effectiveness, and scalability. It includes chapters that address the developments on mining complex types of data.

Edward Conley, William J. Brammar

Christopher J. Coulson

Peter L. Forey, Christopher J. Humphries, Ian J. Kitching, R. W. Scotland, D. J. Siebert, D. M. Williams

David Fell

Kimura

M.F. Perutz

Tim Bugg Enzyme catalysis is a topic of fundamental importance in organic, bio-organic and medicinal chemistry. This book provides an introduction to the underlying principles and mechanisms of enzyme and coenzyme action from a chemical perspective.

Thomas E. Creighton This text provides a comprehensive description of the molecular, chemical and physical properties of proteins. Coverage includes biosynthesis, evolution dynamics, ligand binding and catalysis, in addition to structure. Revised and updated exercises and problems are also featured.

Joint Formulary Committee

Donald E. Knuth Presents basic programming concepts and techniques. This book focuses on the representation of information inside a computer, the structural relationships between data elements, and how to deal with them efficiently. It gives elementary applications to simulation, numerical methods, symbolic computing, software and system design.

Alfred D. French, John W. Brady

Peter Willett

Edward Conley, William J. Brammar

Vincent Laudet, Hinrich Gronemeyer The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format and are researched and compiled by experts in the field.
This Factsbook is devoted to nuclear receptors. The first section presents an introduction and describes the mode of action of the receptors in general. The second section of the book contains detailed entries covering each type of receptor.

Entries provide information on:
Nomenclature and structure
Isolation
DNA binding properties
Ligands
Expression
Target genes
Knockouts
Disease association
Gene structure, promoter and isoforms
Chromosomal location
Amino acid sequences
Key references

Axel T Brunger

William J. Brammar

Katherine A. Fitzgerald, Luke A.J. O'Neill, Andy J.H. Gearing, Robin E. Callard Completely revised and expanded, this second edition of The Cytokine FactsBook is the most up-to-date reference manual available for all current well-characterized interleukins, cytokines, and their receptors. An additional 52 cytokines are included, doubling the number of entries from the previous edition. The key properties of each cytokine are described and presented in a very accessible format with diagrams for each of the receptors.
The Cytokine FactsBook includes free online access to the regularly updated Cytokine Webfacts. Cytokine Webfacts is a web-based comprehensive compendium of facts about cytokines and their receptors that includes a variety of data representations, such as text, signal pathway diagrams and 3D images. This exciting resource is integrated into other databases via hypertext links to provide a unique network, and contains a web-enabled version of RasMol for viewing structures.

Maryadele J. (editor) O'Neil

John W. Crabb

Ian H. Witten, Eibe Frank As with any burgeoning technology that enjoys commercial attention, the use of data mining is surrounded by a great deal of hype. This book includes comprehensive information on neural networks. It features a section on Bayesian networks.

Jerry B. Hook, George Poste

Michael Healy This textbook provides an introduction to the basis of matrix theory. It has been re-written and revised to take account of developments in statistical practice. The more difficult topics have been expanded and the mathematical explanations have been simplified. Vectorising, matrix calculus and complex numbers are also covered.

Roderick D.M. Page, Edward C. Holmes Taking the phylogenetic tree as the central metaphor of evolution, this text develops a phylogenetically based approach to molecular evolution that aims to enable students to see both the evolutionary relevance of molecular data, and the relevance evolutionary theory has for molecular studies.

Luellmann

Jennifer Karns Alexander

M. P. Allen, D. J. Tildesley Computer simulation is an essential tool in studying the chemistry and physics of liquids. Simulations allow us to develop models and to test them against experimental data, and can be used to evaluate approximate theories of liquids. This book presents an introduction to the molecular dynamics and Monte Carlo methods.

N. Darby, Thomas E. Creighton

Martin H. Johnson

Parveen Kumar, Michael Clark

Robert R. Sokal, F.James Rohlf Offers students with little background in statistical analysis an introduction to a variety of statistical concepts and methods. In addition to the incorporation of computer calculation, this new edition expands on a number of important topics, including the revised Kolmogrov-Smirnov test.

Julius H. Comroe

Cedric A. Mims, Anthony Nash, John Stephen Infectious diseases can be caused by bacteria, parasites, viruses, and other microbes such as fungus. This book provides a picture of the global burden of infectious disease, and covers the mechanisms for spread of disease, immune response, and recovery. It is suitable as a course text for graduate and undergraduate students.

Stephen Wolfram

M. Go, P. Schimmel

John E. Cooper Professor A pocket-book version of the international psychiatric classification. It is designed to be an accessible reference to the WHO compiled classification system (ICD-10) for psychiatric and behavioural disorders. It brings together the Glossary with the Diagnostic Criteria for Research and diagnostic notes extrapolated from the Diagnostic Criteria.

H. Jackson Knight

Jonathan L. Haines, Margaret A. Pericak-Vance

T Cormen, C Leiserson, R Rivest, C Stein Not available in the U.S or Canada. International Student Paperback Edition. A new edition of the essential text and professional reference, with substantial new material on such topics as vEB trees, multithreaded algorithms, dynamic programming, and edge-base flow.

Klaus Ebert, Hanns Ederer, Thomas L. Isenhour

B. D. Hames This text presents the best methods, hints and tips for core procedures such as one-dimensional polyacrylamide gel electrophoresis, isoelectric focusing, two-dimensional gel electrophoresis, preparative gel electrophoresis, and peptide mapping, with refinements and updates of the procedures.

Andrew R. Leach, V.J. Gillet

Wayne A. Hendrickson

Maryadele J. O'Neil The Merck Index is a one-volume encyclopedia of chemicals, drugs and biologicals that contains more than 10,000 monographs. Each monograph in this authoritative reference source is a concise description of a single substance or a small group of closely related compounds.

Compounds included:

•       human and veterinary drugs

•       biotech drugs and monoclonal antibodies

•       substances used for medical imaging

•       biologicals and natural products

•       plants and traditional medicines

•       nutraceuticals and cosmeceuticals

•       agriculturals, pesticides and herbicides

•       Organic chemicals used in research

•       Food additives and supplements

•       dyes, colors and indicators

•       environmentally significant substances

Information provided:

•       chemical, common and generic names

•       Over 15,000 trademarks and associated companies

•       CAS Registry Numbers for over 12,000 compounds

•       Over 8,500 chemical structures

•       molecular formulae, weights and percentage composition

•       capsule statements identifying compound classes and scientific significance

•       scientific and patent literature references

•       physical and toxicity data

•       therapeutic and commercial uses

•       caution and hazard information

In addition, there are more than 700 new and completely revised monographs, thousands of new references, trademarks and uses added to existing monographs.  Now includes a companion CD-ROM which features 989 monographs no longer available in print, organic name reactions, supplemental tables and a new user interface for user-friendly searching.

Features of the CD: Searchable by keywords, references, and numerical propertiesSearch the complete contents of the 14th edition, plus nearly a thousand monographs archived from previous editionsComes with a free one-year subscription to the Merck Index Internet EditionWindows-compatible CD powered by CambridgeSoft's ChemFinderExtensively revised supplemental tables now including acronyms, vaccines, and physical constantsMore than 70 pages of hard to find information in one easy-to-use place

Jeff Heaton

David F. V. Lewis This guide to the structure, function and mechanism of the cytochromes P450 focuses on the role of P450s in xenobiotic metabolism and toxicity. Colour illustrations show how modelling of P450s can rationalize their substrate specificity for the metabolism of both endogenous and exogenous chemicals.

Helmward Zollner

Robert K. Scopes

Ian O. Angell, G.H. Griffith

Dr Andrew Leach Introducing the background theory and techniques of molecular modelling, this text also illustrates applications in studying physical, chemical and biological phenomena. It includes simple numerical examples and explanatory figures.

G. W. A. Milne Drugs: Synonyms and Properties provides comprehensive coverage of the 10,000 drugs currently in common use worldwide. Its overall organization and inclusion of detailed chemical information fills an important gap in drug information. This reference, edited by a world-renowned authority in drug design and chemical information and now in its second edition, has become one of the bibles of pharmaceutical research and application.

This book organizes the 10,000 drugs currently in use by therapeutic category. Therefore all tranquilizers, all antidepressants, or all anorexic agents, for example, are grouped together. In all, 204 categories are represented. This arrangement means that all drugs in a given category can be reviewed very easily and their relative properties compared quickly.

A key component of this reference is the extensive coverage of synonyms. The book includes an index of over 30,000 drug synonyms and trade names with a cross-reference to their main entry. This extraordinarily comprehensive view of trade names and generic synonyms makes Drugs: Synonyms and Properties one of the world's most exhaustive references in its field.

For each main entry, the following information is provided: chemical name and a list of trade names and synonyms; the Chemical Abstracts Service (CAS) Registry Number; the European Inventory of Existing Commercial Chemical Substances (EINECS) Number; the Merck Index (Twelfth Edition) Number; the physical properties of each compound; and the known biological activity and indicated applications. Indexes, including a master index of names and synonyms, and of manufacturers and suppliers, are appended.

This reference will be invaluable to research chemists, biologists, and physicians and to anyone interested in drugs who, starting with a single synonym for a drug, will be able to quickly find a thumbnail sketch of the essential information concerning that agent.

Alan Fersht Revised and updated to provide a more general coverage, this third edition of the text is a guide to the study of structure, activity and mechanism in the field of protein science.

Johann Gasteiger, Thomas Engel This first work to be devoted entirely to this increasingly important field, the "Textbook" provides both an in-depth and comprehensive overview of this exciting new area.
Edited by Johann Gasteiger and Thomas Engel, the book provides an introduction to the representation of molecular structures and reactions, data types and databases/data sources, search methods, methods for data analysis as well as such applications as structure elucidation, reaction simulation, synthesis planning and drug design. A hands-on approach with step-by-step tutorials and detailed descriptions of software tools and Internet resources allows easy access for newcomers, advanced users and lecturers alike.
For a more detailed presentation, users are referred to the "Handbook of Chemoinformatics", which will be published separately.

Johann Gasteiger is the recipient of the 1991 Gmelin-Beilstein Medal of the German Chemical Society for Achievements in Computer Chemistry, and the Herman Skolnik Award of the Division of Chemical Information of the American Chemical Society (ACS) in 1997.
Thomas Engel joined the research group headed by Johann Gasteiger at the University of Erlangen-Nuremberg and is a specialist in chemoinformatics.

R.A.D. Williams, etc., P. Singleton, P.A. Lambert

B.W. Kernighan C Programming Language (2nd Edition) [Paperback] Brian W. Kernighan (Author) Dennis M. Ritchie (Author)

Donald J. Birkett

David W. Russell

Frances M. Ashcroft

Dale L. Oxender, C. Fred Fox

Andrew S. Tanenbaum Specifically written for undergraduate students, this best-selling guide provides an accessible introduction to computer hardware and architecture. Updated content is delivered via the familiar structure that has served instructors through four successful editions, with the major addition of an accompanying assembly language instructional CD-ROM.

William Martindale, James E.F. Reynolds, etc.

Tim Wehr, Roberto Rodriguez-Diaz, Mingde Zhu

R K Pathria, Paul D. Beale This text is designed for postgraduate courses in statistical mechanics, and provides a basic grounding in the subject. Graphs illustrate the text and problems have been included to facilitate self-assessment.

Roderick E. Hubbard, Stephen Neidle

Colin Dollery II

Carole A. Bewley, Stephen Neidle

William J. Marshall MA MSc PhD MBBS FRCP FRCPath FRCPEdin FIBiol Dr., Stephen K. Bangert MA MB BChir MSc MBA FRCPath Dr.

Patrick R. Murray, Ellen Jo Baron, James Jorgensen, Michael Pfaller, Marie Louise Landry

Tom M. Mitchell This exciting addition to the McGraw-Hill Series in Computer Science focuses on the concepts and techniques that contribute to the rapidly changing field of machine learning—including probability and statistics, artificial intelligence, and neural networks—unifying them all in a logical and coherent manner. Machine Learning serves as a useful reference tool for software developers and researchers, as well as an outstanding text for college students.

Gerhard Michal

David Webster

Wayne Hendrickson

Thomas E Creighton

Dennis A. Smith, Han van de Waterbeemd, Don K. Walker

Norman Grainger Bisset, Max Wichtl

C.G. Wermuth

Alistair J.P. Brown, Mick F. Tuite

Thomas E Creighton

Frank van Harmelen, Vladimir Lifschitz, Bruce Porter Knowledge Representation, which lies at the core of Artificial Intelligence, is concerned with encoding knowledge on computers to enable systems to reason automatically. This book reviews twenty-five key topics in knowledge representation. It is useful for students, researchers and practitioners in various areas of Artificial Intelligence.

Corwin Hansch, Albert Leo, David Hoekman

Walter Sneader This indispensable work analyzes approximately 150 pharmaceuticals, revealing the key prototype drugs from which all medicinal compounds currently used are derived. A unique "tree and branch" format indicates areas of possible future development as well as areas of neglect.

T. L. Blundell

Alexander McPherson

Wayne A. Hendrickson