Central Dogma
About
The central dogma of biology is that a sequence of DNA
nucleotides is copied to a seqeunce of mRNA nucleotides that serves as
a template for
protein production. The basic concept is essential for even a
rudimentary knowledge of biology.
Central Dogma is meant to
be a simple tool to experiment and practice this concept from a high
school level and up. For instance, the effect of point
mutations and frame shifts on protein sequence can be seen instantly.
The statistics panel provides a way to get a quick look at
the makeup of a protein.
Central Dogma is available for download free of cost.
However, Central Dogma may not be redistributed without
explicit permission from the author.
Download
Version 1.1 (966 kB) January 6, 2008
- Essentially a complete rewrite.
- Sequences are now displayed in configurable columns.
- Counters on sides of sequences.
- Faster and more responsive editing regardless of sequence
length.
- Colored text for nucleotide name, reading frame, and amino
acid type.
- Colors are configurable.
- Statistics are calculated nearly instantly, regardless of
sequence length.
- Translation algorithm is much faster ( O(n) time with
sequence length).
- Highlighting text will show position captions.
Version 1.0 (307 kB) January 3, 2007
Likely Improvements:
- More flexible saving such as saving to rich text.
- Loading sequences via network.
- More coloring analyses.
- Printing Support.
- Undo/Redo Support.
System
Requirements
- Macintosh System Version 10.4 (Tiger) and 10.5 (Leopard).
Screenshots
About/Contact
the Author
I learned object oriented programming and the Cocoa API's while making
the application. I earned a B.S. in Cell Biology and and M.S.
in Immunology from UC Davis and during that time took
a few computer science courses. This application has been
a hobby which somewhat explains why it took just over a year to release
to next version.
I can be contacted at Central_Dogma@mac.com
Thank you taking the time to try Central Dogma and happy translating!
