Colocalization is one of the most frequently cited visual phenomena in modern cell and molecular biological research. It reflects the overlap of signals emitted by various molecules in a multichannel image. CoLocalizer Pro is designed to characterize colocalization objectively. Based on calculation of specialized coefficients, the software performs quantitative determination of the degree of overlap. CoLocalizer Pro helps to obtain crucial information about precise location of the molecules of interest as well as to follow their changes in dynamics. It works with images produced by all major confocal microscopes manufacturers and is highly cost efficient.

CoLocalizer Pro is the only quantitative colocalization analysis software that ensures reliability of coefficients calculations by providing original tools for background correction.

Features

• Works with images obtained by all major brands of confocal microscopes.

• Uses it's unique background correction tools to ensure reliability of quantification.

• Employs published algorithms for instant calculation of all known colocalization coefficients on the selected region of interest (ROI).

• Performs all calculations without the need for a confocal microscope.

• Analyzes image ROI, scatter gram ROI, reveals colocalized and selected pixels, traces pixels of a particular color.

• Exports data in various formats, such as Microsoft Escel, PDF, and HTML.

Designed for Mac OS X

CoLocalizer Pro is a native Mac OS X application written in Cocoa/Objective-C to bring you the best Mac OS X computing experience. It utilizes latest technologies, including high resolution smooth Quartz graphics and system-enabled Help.

Most of CoLocalizer Pro features are accessible directly from the fully customizable toolbar. The toolbar lets you access all frequently used functions of the program easily and quickly. What you need to do is just open the image of interest. CoLocalizer Pro does the rest. It also provides an intuitive, highly efficient Aqua interface to accomplish your tasks with minimum efforts.

Universal support

CoLocalizer Pro is a made to run on both Intel- and PowerPC-based Macs natively. The software will adjust automatically to run at peak performance for your Mac's architecture.

Tools

Requirements:

Minimum Hardware Requirements:

A Mac with an Intel, PowerPC G5 or PowerPC G4 processor.

256 MB of RAM (512 recommended).

Minimum System Requirements:

Mac OS X 10.4 (Tiger).

CoLocalizer Express provides the same working environment as CoLocalizer Pro with scaled-back functionality for students and beginners.

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