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semester 3  
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Lecture 14

DIGESTIVE  (GI) CANCERS

Anatomy :

  • GI tract is the muscular tube from the Mouth to the Anus
  • Sphincters mark change from organ to organ down the line
  • Accesory organs or the GI tract : squirt liquids into the system
  • Duedenom – is the most common place for accessory organs (not a good place for surgery)

Functions of GI Tract:

Ingestion : taking in of food

Propulsion : esophagus moves food along through persitalsis

  • Peristalsis  - waves that move food along
  • Faster movement at the top of the esophagus than at the bottom (moves fast so you can breath again cause when you swallow you stop breathing)
  • Intestines also present with propulsion

Digestion : starts in mouth with break down of carbohydrates through saliva

      • No digestion in esophagus
      • Stomach : digests protein (strong stomach acids)
      • Gall bladder produces bile for fat absorption
      • Small intestine
      • Pancreas
      • No digestion in  colon (large intestine)

Absorption:  small intestine is the main site of absorption (must be very carefull when irradiation in this area)

Elimination: large intestine and colon are responsible for elimination of wastes

  • Site of water absorption which makes the fecal material

Unites States has a high rate of Colon Cancer and a low incidence of stomach cancer

Japan has a high rate of stomach cancer and a low rate of colon cancer

(polyps – convert to cancer is Gardners Syndrome 100% of the time)