Lidocaine NMR Samples
Friday--Feb 15, 2008 Filed in: 333
The latest spectra are
now posted online. The lidocaine specs look
pretty good!! The final product, lidocaine
bisulfate, is not very soluble in CDCl3, which is why
some of you may have observed cloudy NMR sample
solutions. The book uses dimethyl sulfoxide
(DMSO) for the NMR sample, which is much more polar
and better able to dissolve your final product.
We don't have any DMSO currently, so CDCl3 will
have to do; Navid's spectra turned out great in CDCl3
anyway. Just be aware that the chemical shift
values (ppm) for each proton signal will be slightly
different than those reported in your textbook since
chemical shift is solvent dependent.
|
NMR spectra online
Thursday--Jan 31, 2008 Filed in: 333
NMR
spectra for CHEM 333 will be acquired by Maria or
Brooke each week. These spectra are later processed
with iNMR and saved as a
pdf file, which will be posted on this
website. Each student is
responsible for downloading and printing their own
spectra each week. If you would like your spectra
reprocessed, expanded, etc., send me an email and
I'll get right on it. Free versions of iNMR are
available (MAC only). If you'd like to upload your
own data from the server and process it yourself
with iNMR, stop by my office and I'll show you
how.
All of your 1H-NMR spectra for benzocaine looked excellent. Great job on your Fischer esterification. We'll discuss the interpretation of 1H-NMR in class on Friday. See you then.
All of your 1H-NMR spectra for benzocaine looked excellent. Great job on your Fischer esterification. We'll discuss the interpretation of 1H-NMR in class on Friday. See you then.