Table 3. Staging of Malignant Pleural Mesothelioma

• Stage I: Disease confined within the capsule of the parietal pleura: ipsilateral pleura, lung, pericardium, and diaphragm
• Stage II: All of stage I with positive intrathoracic (N1 or N2) lymph nodes
• Stage III: Local extension of disease into the following: chest wall or mediastinum; heart or through the diaphragm, peritoneum; with or without extrathoracic or contralateral (N3) lymph node involvement
• Stage IV: Distant metastatic disease

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