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Software

EvolveAGene3 is a DNA coding sequence evolution simulation program.  Click here to download the EvolveAGene3 package as a Zip archive that include a Universal Macintosh OS X application, a Windows executable program, the Perl source code, and the documentation in pdf format.

CompTrees 4 compares phylogenetic trees with each other and measures their similarity in topology and branch lengths.  Click here to download CompTrees as a Zip archive that includes a Universal Macintosh OSX application, a Windows executable, documentation and installation instructions.

InVitroSimII simulates the Barlow-Hall method of in vitro evolution using StrateGene's GeneMorph II kit.  Click here to download the InVitroSim package as a Zip archive that include a Universal Macintosh OS X application, a Windows executable program, the Perl source code, and the documentation in pdf format.

CodonAlign aligns DNA coding sequences according to an existing alignment of the corrresponding protein sequences by introducing triplet gaps into the DNA sequence at positions of gaps in tthe protein alignment. Phylogenies based on CodonsAligned DNA sequenecs are more accurate than are phylogenies based on dirrectly aligned DNA coding sequences. Click here to download CodonAlign for Macintosh, Windows, and Unix platforms.

TuneClustalX is a utility that facilitates judging tthe quality of alignments constructed by ClustalX and aids in refining those alignments by adjusting gap penalties. Click here to download TuneClustalX for Macintosh, Windows and Unix platforms.